• Dr.Shikha Pahare
• Dr. Kaushilya Sahu

Phytochemical profiling of medicinal plants has emerged as a cornerstone in the search for novel drug candidates. Medicinal plants harbour a wide array of bioactive compounds, including alkaloids, flavonoids, tannins, and terpenoids, which exhibit diverse pharmacological properties. This study underscores the significance of phytochemical screening in identifying potential therapeutic agents to combat global health challenges such as antibiotic resistance, cancer, and metabolic disorders. Employing advanced analytical techniques such as gas chromatography-mass spectrometry (GC-MS), high-performance liquid chromatography (HPLC), and nuclear magnetic resonance (NMR), researchers can unravel the complex phytochemical profiles of medicinal plants with unparalleled precision. Integration of computational methods, including molecular docking and pharmacokinetic modelling, further accelerates the drug discovery pipeline by predicting the bioactivity and safety of plant-derived compounds. Emerging strategies, such as metabolomics and systems biology, enhance the understanding of plant metabolite pathways and their interactions, enabling the identification of novel lead compounds. Furthermore, ethno botanical knowledge serves as a guiding tool, focusing efforts on plants with historically documented therapeutic benefits. While phytochemical profiling holds immense promise, challenges such as variability in plant metabolite concentrations due to environmental factors, limited availability of some plant species, and ethical concerns regarding biodiversity conservation persist. This highlights the need for sustainable and standardized approaches in medicinal plant research. The review advocates a multidisciplinary framework combining traditional knowledge, advanced analytics, and computational tools to harness the therapeutic potential of phytochemicals effectively. Such efforts not only contribute to the development of innovative drugs but also support the preservation of global biodiversity.

Phytochemical profiling, medicinal plants, drug discovery, molecular docking, , biodiversity conservation, etc.

"A Review on Phytochemical Profiling of Medicinal plant for Drug Discovery", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 6, page no.l44-l54, June-2023, Available :http://www.jetir.org/papers/JETIR2306B06.pdf

"A Review on Phytochemical Profiling of Medicinal plant for Drug Discovery", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 6, page no. ppl44-l54, June-2023, Available at : http://www.jetir.org/papers/JETIR2306B06.pdf