• Nikita Prajapati
• Poonam Gautam
• Nitya Chawda
• Shalini Chaturvedi

Coumarin and its derivatives like dicumarols exhibits strong medicinal properties. They show anticoagulants, anti-tumor anti-cancer, anti-inflammatory activities. Researchers works are growing over the years to design more effective drug by synthesis of metal (3d metals) complex using coumarin and dicumorl as ligand. Inspite of this work continue to improve the effectiveness of existing drug (like Ofloxacin; Enrofloxacin etc) and reduce of their dose quantity. Co-coordination with metal ligand complex; drug shows enhanced antimicrobial, anti-bacterial activities. In this review article we discussed about the synthesis of heterocyclic metal-complex in coordination with various drugs; several methods used for complex characterization, biological aspect of the drug co-ordinates metal complexes and their applications.

Antimicrobial, anti-bacterial, Metal complex, antimicrobial activity, Coumarin, Dicumarol.

"A Mini Review: Antibacterial and Antimicrobial application of derivative Dicoumarol metal Complexes in coordination with drugs", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.d709-d722, July-2023, Available :http://www.jetir.org/papers/JETIR2307390.pdf

"A Mini Review: Antibacterial and Antimicrobial application of derivative Dicoumarol metal Complexes in coordination with drugs", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppd709-d722, July-2023, Available at : http://www.jetir.org/papers/JETIR2307390.pdf