• Anupama Baby Chandrasekharan
• Dr E Brindha

Cardiovascular disease research is one of the heavily concentrated areas in biomedical sciences as these group of disorders affecting the heart and blood vessels are the leading cause of mortality and morbidity worldwide. Research on cardiovascular disease should therefore focus on distinct etiological variables involving genetic and epigenetic factors, different pathophysiological pathways used in disease circumstances, and responses to various therapeutic approaches. Such research outcomes are provided through pre-clinical and clinical trials for future consideration. Such conclusions are equally based on in vitro and in vivo experiments. To explore the in vivo research on cardiovascular illnesses, animal models are used. Therefore, choosing an appropriate animal model is a crucial component of any biological investigation. A combination of in vitro and in vivo experiments in several animal models can produce high-quality research output, even when no one animal model is sufficient to produce a scientific notion about the pathophysiology, aetiology, and therapeutic response of the illness condition. Rats are a commonly used animal model in cardiovascular research, and several rat strains are now readily available, created specifically for research. Effectively aiding in this process are transgenic animals. In order to conduct cardiovascular disease research, a variety of rat strains are currently accessible. A researcher must choose a good rat strain by taking into account the type of research being conducted, the availability of the animal, the cost-effectiveness of the study, and other criteria. The albino Wistar rat is a popular model animal for cardiovascular research, and this review article will focus on the settings under which it performs well and the responses it displays. Key words: Cardiovascular disease, Albino Wistar rats, Animal model

Key words: Cardiovascular disease, Albino Wistar rats, Animal model

"Albino Wistar Rat Models in Cardiovascular Disease Research ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.e30-e44, July-2023, Available :http://www.jetir.org/papers/JETIR2307404.pdf

"Albino Wistar Rat Models in Cardiovascular Disease Research ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppe30-e44, July-2023, Available at : http://www.jetir.org/papers/JETIR2307404.pdf