• Dr.Preeti Kulkarni
• Ms.Bhakti Patil
• Mr.Yogesh Hadal
• Mr. Shivam Amare
• Dr.Vaidhun Bhaskar

Proteins and peptides (PPs) have increasingly gained popularity as beneficial particles because of their great selective ability and adequacy with hardly any adverse consequences than tiny atomic medications. Parenteral treatment is frequently employed to treat restorative PPs because of the poor soundness and confined porousness of the GI tract and epithelia. The oral route of medicine delivery is still favored, especially in comparison to parenteral courses. Long-lasting metabolic disease diabetes mellitus necessitates routine subcutaneous insulin infusions. In any event, this organizational method may be linked to patient discomfort and adjacent tissue contamination. Given that oral insulin administration is more likely to be consistent and comfortable for patients, and that it is also more affordable, it has been viewed as a more effective technique for treating diabetes. In any case, different organic hindrances obstruct the clinical interpretation of oral insulin. As an alternative to such infusions, MIT engineers have worked with researchers from Novo Nordisk to create a new pharmaceutical capsule that can administer insulin or other protein sedatives while shielding them from the harsh environment of the gastrointestinal tract. Today when the case arrives at the small digestive system, it separates to uncover dissolvable microneedles that append to the gastrointestinal divider (intestinal wall) and delivery drug for take-up into the circulation system. Massachusetts Institute of Technology (MIT) researchers invented a distinct capsule framework suitable for delivering framework containing intact microneedles (MN). These systems have the potential to facilitate the transportation of a range of medications with the help of a preferred part of the digestive system.

Proteins and peptides (PPs); Diabetes mellitus; subcutaneous injections; Epithelia; Gastrointestinal (GI); Microneedle (MN)

"EMERGING TECHNOLOGY AS MICRONEEDLE PILL FOR ORAL PROTEIN (INSULIN) DELIVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.e162-e168, July-2023, Available :http://www.jetir.org/papers/JETIR2307417.pdf

"EMERGING TECHNOLOGY AS MICRONEEDLE PILL FOR ORAL PROTEIN (INSULIN) DELIVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppe162-e168, July-2023, Available at : http://www.jetir.org/papers/JETIR2307417.pdf