• Sakshi Gupta
• Seema sahu
• Dr. OP Agrawal

This study investigates the potential of Aconitum Hetrophyllum ointment as a 1 percent topical formulation for treating dermatophytosis. Aconitum Hetrophyllum exhibits fungicidal action against a broad spectrum of dermatophytes, moulds, and dimorphic fungi. The research aims to develop an effective treatment option for various human skin conditions caused by dermatophytes. The drug release kinetics of the ointment were analyzed using Higuchi and Korsmeyer-Peppas models, with the Higuchi model showing a close fit to the drug release profile. The graphical representation of the drug release further supports the suitability of the Higuchi model. Future investigations will explore formulations with different base compounds and assess their mechanical properties and clinical efficacy. This research highlights the promising role of Aconitum Hetrophyllum ointment as a potential treatment for dermatophytosis, offering a novel therapeutic approach in dermatological care.

Aconitum Hetrophyllum, dermatophytosis, topical ointment, drug release kinetics, Higuchi model, Korsmeyer-Peppas model, skin conditions, therapeutic approach.

"Phytopharmacological Investigation,Evaluation Of Plant Aconitum Hetrophyllum", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.g572-g595, July-2023, Available :http://www.jetir.org/papers/JETIR2307681.pdf

"Phytopharmacological Investigation,Evaluation Of Plant Aconitum Hetrophyllum", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppg572-g595, July-2023, Available at : http://www.jetir.org/papers/JETIR2307681.pdf