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July-2023
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Journal of Emerging Technologies and Innovative Research ( An International Scholarly Open Access Journal, Peer-reviewed, Refereed Journal )
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UGC Approved Journal no 63975(19)
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UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975
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Published Paper ID:
JETIR2307818
Registration ID:
522232
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Title
PREPARATION AND EVALUATION OF INJECTABLE SCAFFOLD LOADED WITH RALOXIFENE HYDROCHLORIDE FOR BONE REGENERATION
Abstract
Bone injury is very serious in elder people or osteoporotic patients. This study intended to design an injectable scaffold oxidized sodium alginate/gelatin-based 3D scaffolds loaded with raloxifene hydrochloride as a selective estrogen receptor modulator was essential to make use of its anti-resorptive properties for bone regeneration. The prepared formulae were tested for their in-vitro gelation time, drug release, injectability, viscosity properties, and morphological properties. Results presented that the prepared scaffolds were highly porous, additionally, the scaffold containing drug/OSA-gelatin kneaded complex showed the most controlled drug release pattern with the least burst effect and reached almost complete release at 120 h.
Key Words
Raloxifene hydrochloride, gelatin, oxidized alginate, osteoporosis, injectable scaffold, bone regeneration, bone injury.
Cite This Article
"PREPARATION AND EVALUATION OF INJECTABLE SCAFFOLD LOADED WITH RALOXIFENE HYDROCHLORIDE FOR BONE REGENERATION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.i109-i122, July-2023, Available :http://www.jetir.org/papers/JETIR2307818.pdf
ISSN
2349-5162 | Impact Factor 7.95 Calculate by Google Scholar
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Cite This Article
"PREPARATION AND EVALUATION OF INJECTABLE SCAFFOLD LOADED WITH RALOXIFENE HYDROCHLORIDE FOR BONE REGENERATION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppi109-i122, July-2023, Available at : http://www.jetir.org/papers/JETIR2307818.pdf
Publication Details
Published Paper ID: JETIR2307818
Registration ID: 522232
Published In: Volume 10 | Issue 7 | Year July-2023
Page No: i109-i122
Country: VADODARA, GUJARAT, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication
Published Paper URL :: https://www.jetir.org/view?paper=JETIR2307818
Published Paper PDF: https://www.jetir.org/papers/JETIR2307818
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