• Nayan Anant Akhare
• Shivani Sanjay joshi

This review article aims to provide a overview of role of genetic variations in drug response and it’s implication for personalized medicines. It will discuss the current understanding of genetic variations affecting drug metabolism, efficacy, and adverse reactions. Pharmacogenetics and pharmacogenomics are two new field of study that have infinite of potential in medicine discovery and its therapy. Its goal is to come up with ultimate ways to enhance the drug therapy based on their genetic makeup of the patient, and confirming its effectiveness with the negligible side effects. It is the science which analyses the single gene interaction with medications across entire genome.

pharmacogenomics, drug delivery, genes affecting drugs, personalized medicines, pharmacogenetics

"pharmacogenomics: The Role of Genetic Variations in Drug Response ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.i307-i316, July-2023, Available :http://www.jetir.org/papers/JETIR2307840.pdf

"pharmacogenomics: The Role of Genetic Variations in Drug Response ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppi307-i316, July-2023, Available at : http://www.jetir.org/papers/JETIR2307840.pdf