• Kokila Sivasangarn
• Adhithya,K
• Anuradha, R

Dental caries and other gum and tooth issues have long been treated using herbal medicines. In the current microbiological investigation, medicinal plants (Solanum xanthocarpum) were tested for their ability to combat three pathogenic bacteria in the oral cavity (Candida albicans, E. coli and Staphylococcus aureus). Solanum xanthocarpum were used to make ethanolic extract concentrations (50 µg/ml, 100 µg/ml, 150 µg/ml, and 200 µg/ml).The agar well diffusion method was used to assess the antimicrobial effectiveness of the ethanolic extract concentrations of Solanum xanthocarpum, and the inhibition zone size was determined in millimeters. The acquired results demonstrated that the width of the zone of inhibition increased with an increase in extract content, and the antimicrobial activity of the Solanum xanthocarpum ethanolic extracts was detected. Antioxidant activity of extract was assessed by 1,1-diphenyl2- picrylhydrazyl (DPPH) and nitric oxide radical scavenging assays. The extract scavenged DPPH and Nitric oxide radical scavenging assay radicals dose dependently with an inhibitory concentration value of 45.66 and 7.37 µg/ml, respectively. The studied extracts from Solanum xanthocarpum was successful in combating the germs that cause tooth caries.

solanum xanthocarpum, Agar well diffusion, DDPH, Nitric oxide scavenging assay.

"EVALUATION OF ANTIMICROBIAL EFFICACY OF Solanum xanthocarpum AGAINST PATHOGENICMICROORGANISMS IN ORAL CAVITY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.j303-j315, July-2023, Available :http://www.jetir.org/papers/JETIR2307941.pdf

"EVALUATION OF ANTIMICROBIAL EFFICACY OF Solanum xanthocarpum AGAINST PATHOGENICMICROORGANISMS IN ORAL CAVITY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppj303-j315, July-2023, Available at : http://www.jetir.org/papers/JETIR2307941.pdf