• Dr Pallavi C P
• Dr Roopesh Salunke
• Dr Sandeep M
• Dr Shivaswamy P M

Cognitive decline, memory loss (Smritinasha), and poor thinking are the hallmarks of Alzheimer's disease (AD), a progressive neurological illness that significantly lowers the quality of life for older adults. According to the ancient Indian medical system known as Ayurveda, Smritinasha is a sign of disordered mental abilities, mostly brought on by a decline in Medha (intellect) and vitiation of Vata dosha. Classical Ayurvedic scriptures recommend Brahmi Ghrita, a traditional polyherbal medicinal ghee preparation with Bacopa monnieri (Brahmi) as its main constituent, to improve memory, cognition, and brain health.The pharmacological characteristics, neuroprotective benefits, and therapeutic significance of Brahmi Ghrita in the treatment of Alzheimer's disease are examined in this comprehensive study. Its antioxidant, anti-inflammatory, and cholinergic modulatory properties are shown by evidence from Ayurvedic literature, animal models, and contemporary clinical studies. These properties are crucial for treating the pathophysiology of AD. Additionally, research indicates that Brahmi Ghrita may assist neuroregeneration, enhance synaptic connectivity, and lessen the production of amyloid plaque. However, the generalisability of its effectiveness in conventional AD treatment procedures is limited by the lack of extensive, randomised controlled studies.The possibility of using Brahmi Ghrita as a supplementary treatment in early-stage Alzheimer's disease is highlighted in this publication, which also calls for further multidisciplinary research to confirm its effectiveness and standardise formulations for wider clinical uses.

Brahmi Ghrita , Smritinasha , Alzheimer’s disease , Ayurveda , Bacopa monnieri , Cognitive impairment , Neurodegeneration , Medhya Rasayana ,Memory loss , Ayurvedic neurology , Vata dosha , Traditional medicine , Herbal nootropics , Antioxidant therapy ,Complementary and alternative medicine

"A critical analysis on the efficacy of brahmi ghrita in the management of smritinasha viz-a-viz Alziemers disease", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.k252-k262, July-2023, Available :http://www.jetir.org/papers/JETIR2307A34.pdf

"A critical analysis on the efficacy of brahmi ghrita in the management of smritinasha viz-a-viz Alziemers disease", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppk252-k262, July-2023, Available at : http://www.jetir.org/papers/JETIR2307A34.pdf