• Nidhi Srivastava
• Neeraj Suyal
• Aditi Singh

Abstract : The human eye has a unique as well as complex anatomy and physiology due to which there is a great challenge for the researcher as well as for the pharmacologist to provide a controlled drug delivery. Low drug contact time and the poor bioavailability due to the drainage of solution, tear turnover, lacrimation and its dilution are the problems associated with the conventional system. Development of new strategies for delivering of drug to the eye has been continuously done, it has been found that the research advancement in pharmaceutical science have led to the development of new strategies in delivering the drug to anterior segment where as it is difficult for delivering the drug to the posterior segment. Designing of the new delivery system for the anterior segment generates a high drug level, maintains prolonged and effective concentration with minimal or no side effect. Nanotech system are used to deliver the drug to the anterior segment is a new approach. This review provides an overview of anterior segment drug delivery barrier, Nano carriers for anterior segment, disposition of Nano carrier following topical application, Nano-carriers in clinical trials, safety and toxicity as well as the application of the Nano medicines for therapies to the anterior segment diseases.

"Nanotechnology based strategies for the treatment of anterior segment ocular disease ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.c395-c404, August-2023, Available :http://www.jetir.org/papers/JETIR2308246.pdf

"Nanotechnology based strategies for the treatment of anterior segment ocular disease ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppc395-c404, August-2023, Available at : http://www.jetir.org/papers/JETIR2308246.pdf