• MS.KARPE POOJA ASHOKRAO
• Dr. S. R. LAHOTI

During past few years many conventional dosage forms are rapidly being replaced by novel controlled release drug delivery system in which sustained release drug delivery system has gaining more popularity because of its excellent advantages over conventional one such as, reduction in dosing frequency, reduced fluctuation in circulating drug levels, more uniform effect, maximum utilization of drug, improved bioavailability, increased patient compliance, etc. Sustained release system is considered as a wiser approach for the drug with short half-lives and which require repeated dosing, they are easy to formulate and are irrespective of absorption process from gastrointestinal tract after oral administration. Sustained release systems include any drug-delivery system that achieves slow release of drug over an extended period of time. Sustained release drug delivery system provides better therapeutic advantages over traditional drug delivery system. The basic rationale of sustained drug delivery system optimizes of the biopharmaceutical, pharmacokinetic and pharmacodynamics properties of the drug in such a way that utility is maximized, side-effects are reduced and cure of the disease is achieved. The present article is a brief review on various formulation approaches for Sustained release drug delivery system.

Sustained release drug delivery system, Dose frequency, Biological half-life, Physicochemical properties of drug.

" A CONCISE REVIEW ON SUSTAINED RELEASE DOSAGE FORM ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.d213-d222, August-2023, Available :http://www.jetir.org/papers/JETIR2308329.pdf

" A CONCISE REVIEW ON SUSTAINED RELEASE DOSAGE FORM ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppd213-d222, August-2023, Available at : http://www.jetir.org/papers/JETIR2308329.pdf