• Y. Sudheer
• Asupatri Usha Rani

The study investigated the impact of cadmium exposure and the combined influence of manganese (Mn) and cobalt (Co) on the levels of oxidant enzymes in male albino rats. The results revealed a significant increase in oxidant enzyme levels in the cadmium-exposed group compared to the control group (*p<0.05 Vs Control). However, the group exposed to both cadmium and Mn + Co exhibited a noteworthy reduction in these oxidant enzyme levels when compared to the cadmium-exposed group. Intriguingly, no significant difference in oxidant enzyme levels was observed between the control and Mn + Co groups (#p<0.05 Vs Cadmium). These findings suggest that cadmium exposure leads to an elevation of oxidant enzymes, indicative of oxidative stress, and that the combined treatment with Mn + Co effectively mitigates this effect. The protective influence of manganese and cobalt against oxidative stress caused by cadmium holds potential implications for counteracting cadmium-induced toxicity. This research contributes to the understanding of mechanisms underlying cadmium toxicity and highlights the promise of using manganese and cobalt to alleviate its adverse effects in the context of oxidative stress in male albino rats..

Cadmium, Toxicity, Manganese and cobalt, Protective effects, Oxidative enzymes

"MITIGATING CADMIUM TOXICITY THROUGH MANGANESE AND COBALT: EMPHASIS ON OXIDATIVE STRESS IN MALE ALBINO RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.d287-d291, August-2023, Available :http://www.jetir.org/papers/JETIR2308336.pdf

"MITIGATING CADMIUM TOXICITY THROUGH MANGANESE AND COBALT: EMPHASIS ON OXIDATIVE STRESS IN MALE ALBINO RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppd287-d291, August-2023, Available at : http://www.jetir.org/papers/JETIR2308336.pdf