• Dr.G.vijaya sindhuri

Novel drug delivery system plays a pivotal role in delivering the therapeutic drug candidate to the target site to elicit the biological response with a sustained and controlled fashion. The recent advances in molecular biology, genomics, and combinatorial technology speed up the drug discovery process to produce the novel compounds in en masses. But these new molecules pose the pharmacokinetic obstacles in laboratory such as low solubility and poor stability etc. The conventional drug delivery system leads to several problems and those are overcome by controlled release formulation. With this objective, this paper deals with microscope formulation and its advantages since microsphere is unity of the important advanced targeted drug delivery system. The microspheresare solidpowders for free flowing, which composed of proteins or synthetic polymer which are highly biodegradable.They have particle size in range between 1um-1000um that can be delivered by several routes like oral, parenteral, nasal, ophthalmic, transdermal,colonal etc.this review article describes the basic principle of microsphere formulation, methodology of preparation, application in pharmaceutical sciences.

Microspheres, Novel drug delivery, Biodegradable polymer, Therapeutic efficacy.

"MICROSPHERES: A VERSATILE DRUG CARRIER IN NOVEL DRUG DELIVERY SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.e614-e631, August-2023, Available :http://www.jetir.org/papers/JETIR2308472.pdf

"MICROSPHERES: A VERSATILE DRUG CARRIER IN NOVEL DRUG DELIVERY SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppe614-e631, August-2023, Available at : http://www.jetir.org/papers/JETIR2308472.pdf