• Nishat Fatima
• Qamaruddin
• Munawwar Hussain kazmi

ABSTRACT Aloe Vera is one of the oldest medicinal plant and also considered as wonder plant because of its wide range of properties and uses. It is a main ingredient in many herbal medicines and many cosmetic products that are prepared now days. It has been used externally as well as internally in various disease conditions such as wound, burn, skin problems, spleen enlargement, liver diseases, asthma, jaundice, ulcers, constipation, helps in IBD, gastric and duodenal ulcer, and rheumatoid arthritis. Aloe is the dried juice of the leaves of Aloe barbadensis miller. It belongs to Liliaceae family. It contains many chemical constituents Vitamin A, C and E, enzymes such as carboxypeptidase, cellulase, lipase, alkaline phosphatase, brady kinase, anthraquinone, sugars like Acemannan and glucomannan, organic acid like salicylic acid, fatty acids like Cholesterol, campesterol, β-sisosterol and lupeol, Arachidonic acid, γ-linolenic acid. Hormones like auxin and gibberellin and minerals such as Calcium, Chromium, Magnesium and Zinc. These chemical constituents have anti-arthritic, anti-inflammatory, anti-oxidant, immunomodulatory and analgesic activity which confers its use in the management of rheumatoid arthritis. In this review paper role of Aloe Vera is elaborated in the management of rheumatoid arthritis focused on its chemical constituents and mechanism of action.

-Aloe Vera, Anti-inflammatory, Immunomodulatory, Rheumatoid Arthritis, Herbal medicine.

"Role of Aloe vera in the management of Rheumatoid Arthritis ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.f193-f199, August-2023, Available :http://www.jetir.org/papers/JETIR2308521.pdf

"Role of Aloe vera in the management of Rheumatoid Arthritis ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppf193-f199, August-2023, Available at : http://www.jetir.org/papers/JETIR2308521.pdf