• VIJAYA KUMAR J
• Dr. Deeparani Urolagin
• Shebin Favaz K
• Athira T R
• Lavanya K R

ABSTRACT Aim: The present investigation aimed to determine the diuretic activity of Shankapushpi ethanolic extract in Wistar rats. INTRODUCTION Clitoria ternatea (Fabaceae) generally known as Butterfly pea. The condiment Clitoria ternatea L. generally known as butterfly pea showed its anti-inflammatory action in macrophage cells by suppressing inflammatic due to presence of polyphenols. Kaempferol, B- sitosterol, Sankhapushpine, N- hexaconazole, and Hydroxy cinnamic acid are major chemical constituents. it helps in enhancing diuretics, attention, learning capabilities, internal fatigue, wakefulness, stress, anxiety, depression, etc. and has been extensively screened for different pharmacological activities. METHODOLOGY The ethanolic extract of Clitoria ternatea (leaves) were orally administered to mainly Wistar rats. Furosemide were used as diuretic reference. Urine output was recorded up to 5 hours. the urinary excretion rate and Ph and electrolyte was determined. Toxic study was carried out to determine the cure of the medicine and phytoconstituents presence was analyzed by phytochemical tests. RESULTS Phyto chemical evaluation revealed the presence of alkaloids, carbohydrates, tannins, phenols, and terpenoids. CONCLUSION This study will give a quantitative base for explaining the natural medicinal use of Clitoria ternatea as a diuretic agent, promoting the safe diuretic excretion process.

Clitoria ternatea, Butterfly pea, diuretic.

"EVALUATION OF DIURETIC ACTIVITY OF SHANKAPUSHPI ETHANOLIC EXTRACT IN WISTAR RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.g844-g851, August-2023, Available :http://www.jetir.org/papers/JETIR2308696.pdf

"EVALUATION OF DIURETIC ACTIVITY OF SHANKAPUSHPI ETHANOLIC EXTRACT IN WISTAR RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppg844-g851, August-2023, Available at : http://www.jetir.org/papers/JETIR2308696.pdf