• Nikhil Patel
• Nitya Chawda
• Deepika Gautam
• Poonam Gautam
• Vibha Kunji

In a more environmentally friendly procedure than the standard one, a Schiff base and its transition metal complexes of Ni2+, Zn2+, and Cu2+ were produced. Through elemental and spectroscopic investigations, the structures of novel compounds have been identified and clarified. Schiff bases with a functional group of imines or Azomethine (-C=N-) are flexible Pharmacophores. Due to their extensive uses in Pharmacology as Anti-viral, Anti-bacterial, Anti-fungal, Anti-malarial, Anti-tuberculosis, Anti-cancer, and Anti-HIV agents. Schiff base metal Complexes for the treatment of several diseases that are challenging to treat with previously used conventional methods. We focus on the Six compounds with Cu2+, Zn2+, Ni2+ content that have antimicrobial action against both gram-positive and gram-negative bacteria. None of these complexes have previously been reported. Novelty: The coordination of metal complexes with Streptomycin Drug (1000 mg/ml) creates a technique for the synthesized of novel drugs while also improving the activity of presently used Streptomycin. Current work Supports that Using Conventional new Solvent free Grinding & Using Solvent use Staring Method. These complexes might make it possible to lower the dosage of medication that is given to the body.

"Efficient Synthesis of some benign Schiff’s base Metal Complexes and their Anti-microbial activities", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 9, page no.d66-d75, September-2023, Available :http://www.jetir.org/papers/JETIR2309308.pdf

"Efficient Synthesis of some benign Schiff’s base Metal Complexes and their Anti-microbial activities", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 9, page no. ppd66-d75, September-2023, Available at : http://www.jetir.org/papers/JETIR2309308.pdf