• Dr Rupal Dubey
• Anamika Mary David
• Dr Bhaskar Kumar Gupta
• Khushboo Mehandole

Through the design of drug delivery systems and the opening of the possibility of controlling infections at the molecular level, nanotechnology has significantly improved therapeutics. Nanocarriers can cross biological barriers and are able to target cellular reservoirs of Mycobacterium tuberculosis (M. tuberculosis). Systems based on nanoparticles have a lot of potential for treating and preventing tuberculosis (TB). Numerous nanocarriers have been thoroughly examined as potential drug delivery systems for a range of administration methods. A promising approach to treating TB with enhanced drug absorption and decreased dose frequency involves targeting the pharmaceuticals to specific physiological areas, such as the lymph nodes. By reducing side effects and necessitating less frequent dosing regimens, nanotechnology-based rational targeting may increase treatment success. Ultimately leading to improved levels of adherence and more patient compliance. The current paper gathers the fundamental physiological characteristics of the illness as well as recent advancements in the study of nanoparticles used to treat tuberculosis.

Mycobacterium tuberculosis, Nanocarriers, Nanoparticles, Drug delivery, Antituberculosis drugs

"Targeted Nanoparticle Based Interventions for the Management of Tuberculosis – A Holistic Approach", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 9, page no.e453-e475, September-2023, Available :http://www.jetir.org/papers/JETIR2309454.pdf

"Targeted Nanoparticle Based Interventions for the Management of Tuberculosis – A Holistic Approach", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 9, page no. ppe453-e475, September-2023, Available at : http://www.jetir.org/papers/JETIR2309454.pdf