UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
Call for Paper
Volume 11 | Issue 5 | May 2024

JETIREXPLORE- Search Thousands of research papers



WhatsApp Contact
Click Here

Published in:

Volume 10 Issue 10
October-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

7.95 impact factor calculated by Google scholar

Unique Identifier

Published Paper ID:
JETIR2310389


Registration ID:
526253

Page Number

e607-e614

Share This Article


Jetir RMS

Title

EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OFAQUEOUS AND ALCOHOLIC EXTRACTS OF LEAVES OF Epipremnum aureum.linn IN RATS

Abstract

Background: Epipremnum aureum (Family Araceae) commonly known as Money plant is a vigorously growing in India. It is a common indoor plant generally used for ornamental purposes having indoor air pollution removing capacity. The preliminary phytochemical studies of the aqueous and alcoholic extracts of the leaves showed the presence of various phytochemical constituents such as alkaloids, tannins, flavonoids, triterpenoids, and saponins. Aims and Objectives: The aim of the present study was carried out with the objective of phytochemical screening and to evaluate the anti-inflammatory and analgesic of aqueous and alcoholic extract of E.aureum in albino rats. Materials and Methods: Albino Wistar rats (100–150 g body weight) were used in this study. Aqueous and alcoholic extract of Epipremnum aureum was used to evaluate acute anti-inflammatory and analgesic activity by plethysmometer and hot plate method by oral administration at doses of 200 mg/kg body weight in healthy albino rats. Results: In acute studies, the aqueous and alcoholic extract showed anti-inflammatory activity by significant reduction in the paw edema volume, and significantly increased the latency of paw licking in hot plate method in a dose-dependent manner when compared with the control and standard drug. Statistical analysis was carried out by one-way ANOVA test. Conclusion: Thus, the positive results suggest that Epipremnum aureum extracts should be further studied to determine the bioactive chemical compounds as well as to understand the possible mechanism of action and evaluate their toxicity looking towards pharmaceutical actions.

Key Words

Epipremnum aureum, Anti-inflammatory; Analgesic; Carrageenan -induced Paw Edema, Hot plate

Cite This Article

"EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OFAQUEOUS AND ALCOHOLIC EXTRACTS OF LEAVES OF Epipremnum aureum.linn IN RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 10, page no.e607-e614, October-2023, Available :http://www.jetir.org/papers/JETIR2310389.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OFAQUEOUS AND ALCOHOLIC EXTRACTS OF LEAVES OF Epipremnum aureum.linn IN RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 10, page no. ppe607-e614, October-2023, Available at : http://www.jetir.org/papers/JETIR2310389.pdf

Publication Details

Published Paper ID: JETIR2310389
Registration ID: 526253
Published In: Volume 10 | Issue 10 | Year October-2023
DOI (Digital Object Identifier):
Page No: e607-e614
Country: Hyderabad, Telangana, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


Preview This Article


Downlaod

Click here for Article Preview

Download PDF

Downloads

00072

Print This Page

Current Call For Paper

Jetir RMS