• Abdul Hafeez
• Mohammad Yusuf Ansari
• Abrar Mohd Khan
• Mohd Danish
• Hamida Bano Ansari

Abstract : Liver disease refers to an inflammatory and pathological condition which may be due to viral infection, autoimmune hepatitis and hepatitis that occurs as a secondary result of medications, drugs, toxins, and alcohol. Autoimmune hepatitis is a disease that occurs when your body makes antibodies against your liver tissue. If symptoms occur with an acute infection, they can appear anytime from two weeks to six months after exposure. Symptoms manifested by fever, fatigue, nausea, vomiting, abdominal pain, anorexia, dyspepsia, irregularity in bowel habits, dull ache in hepatic region, Jaundice, dark urine, light-colored stools Hepatitis, Cirrhosis, Ascites, Haemochromatosis, Hepatic failure etc . In view of high prevalence and absence of any approved therapies, this review was an attempted to explore the efficacy and safety of Dawa-ul-Kurkum in liver disease. Dawa-ul-Kurkum has potential to reduce the symptoms and grading of Hepatic dysfunctions, Anaemia, Ascitis, inflammation of Liver and spleen. There was no any adverse effect observed while using formulation. Hence it can be concluded that the drug Dawa-ul-Kurkum is effective and safe in the management of hepatic dysfunction and it is a novel remedy for the management of liver diseases. It was observed that after different clinical studies, Anorexia, Nausea, Dyspepsia and Heaviness in right hypochondriac region were significantly reduced and drug is effective in relieving symptoms, reduction in body weight and dull ache and dissolving fat from hepatocyte. Ultrasonography of patients shows grade I fatty liver and no patient remains in grade II fatty liver though its results on liver enzymes and lipid profile were insignificant statistically. The safety profiles of Dawa ul Kurkum were evaluated after laboratory investigations which include Complete blood count, Hb%, ESR, Blood Urea, S. Creatinine, SGOT, SGPT, and Alkaline Phosphatase shows significant difference. IndexTerms - Dawa-ul-Kurkum; Hepatic dysfunctions; Anorexia; Unani Medicine; liver disease.

Dawa-ul-Kurkum; Hepatic dysfunctions; Anorexia; Unani Medicine; liver disease.

"Dawa ul Kurkum: An Innovative Hepato-protective Unani Formulation: A Review ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 10, page no.h678-h682, October-2023, Available :http://www.jetir.org/papers/JETIR2310684.pdf

"Dawa ul Kurkum: An Innovative Hepato-protective Unani Formulation: A Review ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 10, page no. pph678-h682, October-2023, Available at : http://www.jetir.org/papers/JETIR2310684.pdf