Abstract
Abstract:
In recent years, antibiotics have been used widely in intensive shrimp culture and this may lead to their contamination of the environment. Surveys on residues of Nitro furan metabolites [AOZ, AMOZ, AHD, SEM], Chloramphenicol in water and mud in shrimp ponds in mangrove areas were conducted in then or this well as in south of Viet Namin July and August,2002.The results show that these antibiotics are found in all samples in both shrimp ponds and surrounding canals. The highest concentrations ofNitrofuranmetabolites[AOZ,AMOZ,AHD,SEM],Chloramphenicolare1.04,2.39,6.06,and2.50ppm in waters amples;and734.61,820.49,2615.96,426.31ppm(based on wet mud weight), respectively. The comparison of antibiotics residues between study sites and types of shrimp ponds will be discussed in this paper. The results also suggest that antibiotics residues may cause harmful effect on ecosystems in the study sites. An analytical method based on LCMS was developed and optimized in order to determine the most useful antibiotics (Nitrofuranmetabolites [AOZ, AMOZ, AHD, SEM], Chloramphenicol) used in aquaculture. A simple extraction procedure, without any clean-up step, was evaluated in order to obtain maximum analyte recovery from shrimp samples (Machobrachiumrosenbergi, Machobrachiummalcolmsoni, Panaeusmonodo, Fenneropanaeusindicus, Litopanaeus Vannamei, and Litopanaeus).