UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 10 Issue 11
November-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2311149


Registration ID:
525190

Page Number

b408-b417

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Title

Production of Lovastatin by Aspergillus flavusNCIM-1028 using Wheat husk under Solid state fermentation

Abstract

Production of lovastatin was carried out by Aspergillus flavus NCIM-1028 using agro-industrial residue paddy straw,as substrate under solid state fermentation. Lovastatin is a potent hypercholesterolemic drug used for lowering blood cholesterol. In recent years,lovastatin has also been reported as a potential therapeutic agent for the treatment of various types of tumours and also play a tremendous role in the regulation of the inflammatory and immune response,coagulation process,bone marrow, neovascularization,vascular tone and arterial pressure.Process parameters like Incubaton time(5-days),Temperature,moisture content(60%),Inoculum age(4 days),Inoculum volume(30%v/w),pH of the medium(6.0),carbon source(1.5%Lactose) and nitrogen source(1.5%Ammonium sulphate) were optimized and gave an overall yield of 11.2mg/gds of lovastatin after optimization.

Key Words

Lovastatin,Aspergillus flavus,paddy straw,solid state fermentation,process parametersoptimization.

Cite This Article

"Production of Lovastatin by Aspergillus flavusNCIM-1028 using Wheat husk under Solid state fermentation", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 11, page no.b408-b417, November-2023, Available :http://www.jetir.org/papers/JETIR2311149.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Production of Lovastatin by Aspergillus flavusNCIM-1028 using Wheat husk under Solid state fermentation", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 11, page no. ppb408-b417, November-2023, Available at : http://www.jetir.org/papers/JETIR2311149.pdf

Publication Details

Published Paper ID: JETIR2311149
Registration ID: 525190
Published In: Volume 10 | Issue 11 | Year November-2023
DOI (Digital Object Identifier):
Page No: b408-b417
Country: Visakhapatnam, Andhra Pradesh, India .
Area: Science & Technology
ISSN Number: 2349-5162
Publisher: IJ Publication


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