UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Volume 10 Issue 11
November-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2311155


Registration ID:
527619

Page Number

b454-b468

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Title

TRANSDERMAL PATCHES AND ‘SKIN-ON-A-CHIP’ MODEL: A REVIEW ON THEIR APPLICATIONS

Abstract

The efficacy of orally administered medications gets affected by multiple pharmacokinetic parameters. So, the technology involving transdermal delivery of medication was developed to enhance the pharmacokinetic qualities and overcome some of the disadvantages related to the oral route of administration. In this article, we have included the history of the transdermal drug delivery system, factors affecting drug permeation through the skin, advantages, limitations, and use in pediatrics and elderly patients. This review article compiles the different models of skin-on-a-chip for drug testing (human skin equivalent models and full-thickness skin equivalent models). The human skin equivalent model utilizes the technique of incorporating a biopsy of the skin. The in-situ skin-on-a-chip is about making the skin model directly in the chip. The most recent scientific research on the applications of skin-on-a-chip technology in drug diffusion studies has been discussed.

Key Words

Transdermal drug delivery, skin on-a-chip model, drug analysis, Full-thickness skin equivalents, drug diffusion

Cite This Article

"TRANSDERMAL PATCHES AND ‘SKIN-ON-A-CHIP’ MODEL: A REVIEW ON THEIR APPLICATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 11, page no.b454-b468, November-2023, Available :http://www.jetir.org/papers/JETIR2311155.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"TRANSDERMAL PATCHES AND ‘SKIN-ON-A-CHIP’ MODEL: A REVIEW ON THEIR APPLICATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 11, page no. ppb454-b468, November-2023, Available at : http://www.jetir.org/papers/JETIR2311155.pdf

Publication Details

Published Paper ID: JETIR2311155
Registration ID: 527619
Published In: Volume 10 | Issue 11 | Year November-2023
DOI (Digital Object Identifier):
Page No: b454-b468
Country: Bengaluru, Karnataka, India, Karnataka, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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