• R VINITHA
• S.UMA MAHESWARI
• SUSAN ALBY

Some new benzimidazole with iso indoline (JV1-JV5) have been synthesized by Leuckart reaction using microwave irradiation. Synthesis of1,4 aryl 1H benzimidazole-2yl alkyl-1H isoindol-1,3-dione compounds by using different aldehydes. The structures of newly synthesized compounds were characterized by FT-IR, 1H NMR, and MASS spectroscopy. The in vitro Anthelmintic activity of the synthesized compounds was studied by using Eudrilluseuginae earth worms. Albendazole was used as standard drug.

Benzimidazole with isoindoline derivatives, leuckart reaction, microwave irradiation, Anthelmintic activity

"SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF BENZIMIDAZOLE WITH ISOINDOLINE DERIVATIVES BY LEUCKART REACTION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 11, page no.c119-c126, November-2023, Available :http://www.jetir.org/papers/JETIR2311218.pdf

"SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF BENZIMIDAZOLE WITH ISOINDOLINE DERIVATIVES BY LEUCKART REACTION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 11, page no. ppc119-c126, November-2023, Available at : http://www.jetir.org/papers/JETIR2311218.pdf