• Venkatesan Karthick
• Abdul Abduz Zahir

Diabetes Mellitus threatens hundreds of millions of the world's population; it is estimated to reach 693 million by 2045. Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that affects millions of people worldwide. Encapsulated nanoparticles (ENPs) are increasingly being used as a potential therapy for T2DM, due to their ability to target and deliver drugs to specific areas of the body. The aim of this review is to investigate the current literature on ENPs for the treatment of T2DM, with a focus on various strategies for controlling the diabetes. A discussion is provided on the advantages of using ENPs in diabetes treatment, as well as the challenges associated with developing drugs for T2DM. There are several types of ENPs, including liposomes, polymeric nanoparticles, nanostructured lipid carriers, and dendrimers, that can be used for the treatment of T2DM. By modifying NPs properties, targeting strategies, and combinations, researchers aim to maximize therapeutic outcomes and minimize adverse effects. ENPs offer enhanced bioavailability compared to traditional drug formulations. The small size of NPs allows them to penetrate through biological barriers, such as the blood-brain barrier and gastrointestinal wall, thereby improving the distribution and accessibility of drugs to the target tissues. This enhanced bioavailability results in improved therapeutic outcomes and reduced dosing requirements. In this article we are discussing about the innovative techniques of ENPs for the management of T2DM. Ongoing research and development initiatives within this sector show considerable potential for improved patient outcomes and chronic disease treatment.

Type 2 diabetes mellitus, Encapsulated nanoparticles, Potential Therapy.

"Strategies for enhancing the efficacy in the treatment of type 2 diabetes mellitus using encapsulated nanoparticles", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 12, page no.e448-e453, December-2023, Available :http://www.jetir.org/papers/JETIR2312456.pdf

"Strategies for enhancing the efficacy in the treatment of type 2 diabetes mellitus using encapsulated nanoparticles", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 12, page no. ppe448-e453, December-2023, Available at : http://www.jetir.org/papers/JETIR2312456.pdf