• Dr. Rananavare Dipa Shivaji
• Dr. Shubhangi Kamble
• Dr. Joydeep Chakraborty
• Hetvi Kanojia
• Jaivik Ghadiya

In Ayurveda, there are two primary methods of medicine administration Antah-Parimarjan (~internal cleansing) & Bahi- Parimarjana (~internal cleansing). Lepa (A paste of herbs application over affected part) is one of the Bahi-Parimarjan Chikitsa. We possess precise knowledge of the effects of Krimighna Gana (10 drugs used against macrobes and microbes) plants, as described in classical Ayurvedic texts. In this experimental study, the efficacy of Krimighna Gana Mahakashaya Lepa (a topical application) is assessed by turning it into nanoparticles and examining its antibacterial strength. over the last decade, we have witnessed transformative changes in the field of nanotechnology. Integration of Ayurveda and nanotechnology may provide the best medicines to treat various life-threatening diseases . The amalgamation of Ayurveda and nanotechnology has the potential to yield optimal pharmaceutical solutions for a wide range of life-threatening ailments. Utilizing nanocarriers to administer Ayurvedic medications and formulations will enhance their efficacy in treating various chronic illnesses. Nanotechnology is an emerging technology that is poised to revolutionize the production process of many items. It is a pioneering scientific field that has recently emerged. Additionally, it can contribute to heightened efficacy and safety concerns linked to medications. These formulations can increase bioavailability and stability, as well as minimize the dose of various potent drugs In the past ten years, researchers have displayed increased interest in this topic. There is a pressing want for a methodical examination of Herbal Nano Medicines for Ayurvedic formulations. Silver nanoparticles (AgNPs) have been proven to possess good antimicrobial activity. Green synthesis of AgNPs has been reported as safe, low cost and ecofriendly Research has demonstrated that silver nanoparticles (AgNPs) exhibit effective antibacterial properties. The process of synthesizing AgNPs using green methods has been documented as being safe, cost-effective, and environmentally beneficial. Considering this backdrop, we chose the issue of researching the conversion of Krimighna gana plant extracts into nanoparticles. This study showcases the effectiveness of silver nanoparticles manufactured by green methods, employing nanotized Krimighna gana plant extracts. The study evaluates the antibacterial strength of these nanoparticles for potential usage in topical applications. This work has the potential to contribute to future progress in the field of Ayurvedic medicines.

Ayurveda, Antimicrobial Potency, Krimighna Gana, Experimental Study, Nanotechnology.

"TO EVALUATE THE EFFICACY OF GREEN SYNTHESIZED NANOTIZED KRIMIGHNA GANA PLANT EXTRACTS USING SILVER NANOPARTICLES BY CHECKING ITS ANTIMICROBIAL POTENCY FOR TOPICAL APPLICATION.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 1, page no.b60-b67, January-2024, Available :http://www.jetir.org/papers/JETIR2401107.pdf

"TO EVALUATE THE EFFICACY OF GREEN SYNTHESIZED NANOTIZED KRIMIGHNA GANA PLANT EXTRACTS USING SILVER NANOPARTICLES BY CHECKING ITS ANTIMICROBIAL POTENCY FOR TOPICAL APPLICATION.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 1, page no. ppb60-b67, January-2024, Available at : http://www.jetir.org/papers/JETIR2401107.pdf