• Mr. Bhimashankar K. Bhui
• Mr. Rahul. I.Jadhav
• Aditya Anil Shelake
• Aarti Ashok Rokade
• Aarti Vikas Panche

Abstract: Controlled drug delivery systems ensure a consistent medication concentration at the absorption site, enabling the homeostasis levels inside the optimal range. This but also reduces side effects but also lessens the need for frequent management. Prolonged release mouth-administered product offer a distinct benefit compared to traditional medication form. They optimize drug attributes, minimizing dosing frequency to a point where a once-daily dose effectively manages therapeutic needs. This approach ensures uniform plasma concentration, maximizing drug utility while minimizing specific and general adverse reactions. It accelerates the treat or manage of conditions in the minimal duration using the little medication amount, promoting greater patient compliance. creation of a regulated drug delivery rate-speed aims to address challenges linked to traditional drug delivery methods. These systems administer the drug at a predefined rate, either locally or throughout the entire system, over a designated duration. Regulated delivery formulations decrease the necessary daily dosing frequency. Over the last two decades, there has been significant progress in regulated medication release mechanism, spanning from comprehensive-scale to nano-scale, incorporating smart precision delivery strategies. Controlled or modified release drug delivery systems enable the gradual administration of drugs over an extended duration. These systems encompass various dosage forms, including those for oral and transdermal use, as well as injectable and implantable options. Although the oral route is generally the preferred method for drug administration, some chemical compounds face challenges like low bioavailability due to solubility or permeability issues.

Keywords: Controlled Drug Delivery System, Transdermal Drug Delivery System, Factors affecting CDDS, Polymers in CDDS

"A Comprehensive Review of Controlled Drug Delivery System", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 2, page no.c307-c326, February-2024, Available :http://www.jetir.org/papers/JETIR2402239.pdf

"A Comprehensive Review of Controlled Drug Delivery System", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 2, page no. ppc307-c326, February-2024, Available at : http://www.jetir.org/papers/JETIR2402239.pdf