• Ansari Aashif Raza Mohd Imtiyaz
• Dr. Deeparani Urolagin
• Vijaya kumar J
• Harish N

Piperine is an alkaloid that belongs to the family of Piperaceae. It is found in various species such as black pepper (Piper nigrum) white pepper and long pepper (Piper). Piperine Natural derived products, which can be extracted from plant origin, have been extensively used in traditional medicine to treat various disorders due to their various pharmacological actions such as antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective, neuroprotective, and increasing bioavailability. In addition, piperine can inhibit enzymes in the liver and intestines such as cytochrome P-450 enzymes & and glucuronosyltransferases. The inhibition of these enzymes helps slow down drug and nutrient metabolism and promotes their absorption. This review provides a comprehensive overview of piperine and its various pharmacological actions.

piperine, Piper nigrum, Piper longum, extract, bioavailability

"An In-Depth Look at the Pharmacological Effects of Piperine", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 2, page no.c766-c786, February-2024, Available :http://www.jetir.org/papers/JETIR2402292.pdf

"An In-Depth Look at the Pharmacological Effects of Piperine", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 2, page no. ppc766-c786, February-2024, Available at : http://www.jetir.org/papers/JETIR2402292.pdf