• Ranveer Singh
• Poonam Bhardwaj
• Naveen Jain
• Muskan Papneja
• Mohan Kumar

Enzyme-mediated nitration has emerged as a promising and sustainable approach in organic synthesis, with a specific focus on heterocyclic compounds. The present work highlights the revolutionary potential of enzyme-mediated nitration in the field of heterocyclic chemistry, underscoring its function as a driving force behind the advancement of the discipline and its contribution to sustainable methods in organic synthesis. Enzymes are a viable option for the regulated nitration of heterocyclic compounds because of their natural selectivity and environmental friendliness. This abstract examines recent advances in substrate scope expansion, regioselectivity control, and enzyme engineering. It also explores the practical ramifications, taking cost-effectiveness, scalability, and incorporation into current synthetic processes into account. The emergence of enzymatic nitration as a groundbreaking approach is accompanied by a clear positive impact on the development of heterocyclic chemistry and the encouragement of sustainable practices in organic synthesis.

Enzyme-mediated nitration, heterocyclic chemistry, sustainable practices, organic synthesis, regioselectivity, substrate scope, enzyme engineering, green chemistry, practical feasibility, scalability, cost-effectiveness, selective synthesis

"Enzyme-Mediated Nitration: A Catalyst for Advancing Heterocyclic Chemistry and Pioneering Sustainable Practices in Organic Synthesis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 2, page no.d640-d649, February-2024, Available :http://www.jetir.org/papers/JETIR2402378.pdf

"Enzyme-Mediated Nitration: A Catalyst for Advancing Heterocyclic Chemistry and Pioneering Sustainable Practices in Organic Synthesis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 2, page no. ppd640-d649, February-2024, Available at : http://www.jetir.org/papers/JETIR2402378.pdf