• Chaithra L

Hyperlipidemia, commonly managed with statins, is a significant contributor to cardiovascular morbidity. While statins are generally safe, the rare complication of rhabdomyolysis, characterized by severe muscle breakdown, poses a serious risk. This case report presents a 48- years old male with a history of ischemic heart disease and recent coronary angioplasty, who developed rhabdomyolysis attributed to atorvastatin (Tab. Tonact). The patient exhibited symptoms of myalgia, weakness, and alarming laboratory abnormalities, leading to acute kidney injury. Utilizing the naranjo scale, the adverse drug reaction was deemed "Probable." The discussion explores the spectrum of statin-induced myopathy, risk factors, and proposed mechanisms. Management involved statin discontinuation, intravenous hydration, and monitoring for improvement. The patient's recovery was complicated by fever and renal complications, ultimately diagnosed as rapidly progressive renal failure. This case underscores the importance of vigilance in statin use, considering risk factors and promptly addressing myopathy symptoms. Clinicians should be aware of alternative lipid-lowering strategies and potential complications, emphasizing the need for patient education and comprehensive risk assessments. The report concludes with recommendations for future statin therapy and underscores the necessity for careful monitoring in high-risk individuals.

Rhabdomyolysis, Statin, Probable, Myopathy, Naranjo scale

"ATORVASTATIN INDUCED RHABDOMYOLYSIS WITH ACUTE KIDNEY INJURY: CASE REPORT", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 2, page no.e80-e84, February-2024, Available :http://www.jetir.org/papers/JETIR2402411.pdf

"ATORVASTATIN INDUCED RHABDOMYOLYSIS WITH ACUTE KIDNEY INJURY: CASE REPORT", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 2, page no. ppe80-e84, February-2024, Available at : http://www.jetir.org/papers/JETIR2402411.pdf