• Dr V K Prabhat
• Rajni kumari
• Dr Ravi Kumar singh

The present paper deals with genomic study in some therapeutic fungi in Gaya District. Fungal genomes are among the smallest genomes of eukaryotes. Some therapeutic fungus i.e Aspergillus fumigatum,Candida albicans, and Cryptococcus neoformans were collected in addjoinig area of Gaya and Bodh Gaya. Fungal sample 5 mL of collection solution was poured on the culture plate, and the fungal mycelium was pelleted in a microcentrifuge tube by centrifugation at 14,000 rpm for 1 min. the supernatant was transferred to a fresh microcentrifuge tube with equal volume of ethanol and vortexed. The lysate was placed in the Spin column and centrifuged at 10,000 rpm for 1 min followed by two washes with 500 μL of wash buffer. The DNA was eluted in 100 μL of elution buffer by spinning at 10,000 rpm for 2 min and was stored at −20 °C till further processing. approximate base pair (Mb)size of band on gel electroforosis in fungus Aspergillus fumigatum, no of chromosome 8 and30Mb, Candida albicans no of chromosome 8 and 16Mb and Cryptococcus neoformans no of chromosome 14 and 19Mb. High levels of fungal DNA with candida albicans but low levels of fungal DNA with Aspergillus fumigagatum.

Kew words: Genomics,Ethanol A. fumigatum,C albicans, and C neoformans.

"GENOMIC STUDY OF SOME THERAPEUTIC FUNGI IN GAYA DISTRICT, BIHAR ,INDIA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 3, page no.b330-b333, March-2024, Available :http://www.jetir.org/papers/JETIR2403142.pdf

"GENOMIC STUDY OF SOME THERAPEUTIC FUNGI IN GAYA DISTRICT, BIHAR ,INDIA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 3, page no. ppb330-b333, March-2024, Available at : http://www.jetir.org/papers/JETIR2403142.pdf