• Nancy Raj
• Rajesh Maurya, Rajendra Kumar Jayswal
• Raj Pal, Rajneesh Tiwari
• Reetesh Malviya , Rishikant Gupta
• Dr.Jagdish Chandra Rathi

The formulation and evaluation of a hydrogel containing a microemulsion of Amphotericin B and Fluconazole represent a novel approach in drug delivery systems. This study aimed to develop a hydrogel formulation that incorporates a microemulsion of Amphotericin B and Fluconazole for enhanced therapeutic efficacy. The hydrogel was prepared using suitable polymers and characterized for various parameters like pH, viscosity, drug content, spreadability, and in vitro release studies. The evaluation of the hydrogel demonstrated promising results in terms of drug content uniformity, sustained release profile, and stability. The developed hydrogel showed potential for controlled drug delivery with improved bioavailability and reduced dosing frequency.

Formulation, Hydrogel, Micro-emulsion, Amphotericin- b, Fluconazole, NDDS.

"Formulation and evaluation of hydrogel containing micro emulsion of Amphotericin- b and Fluconazole", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 3, page no.j599-j606, March-2024, Available :http://www.jetir.org/papers/JETIR2403978.pdf

"Formulation and evaluation of hydrogel containing micro emulsion of Amphotericin- b and Fluconazole", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 3, page no. ppj599-j606, March-2024, Available at : http://www.jetir.org/papers/JETIR2403978.pdf