• Naziya Akhtar
• Steffi Thomas
• Akhlesh Kumar Singhai

The oral route of drug delivery is widely preferred due to its convenience and patient compliance. In the development of drug delivery systems, various components play crucial roles, among which polymers have gained significant importance. Polymers are macromolecular compounds composed of multiple monomer units linked together by chemical bonds. Floating drug delivery systems (FDDS) offer an additional advantage for drugs primarily absorbed in the upper segments of the gastrointestinal (GI) tract, such as the stomach, duodenum, and jejunum. The focus of this review is to elucidate the types of FDDS, the mechanisms employed for achieving gastric retention, and the polymers utilized in these systems. Polymers used in drug delivery systems can be classified into three categories based on their origin: natural, semi-synthetic, and synthetic. Each type of polymer has its own set of advantages and disadvantages. This article specifically discusses the different types of natural, semi-synthetic, and synthetic polymers employed in drug delivery systems. Natural polymers such as guar gum, chitosan, xanthan gum, gellan gum, and sodium alginate are highlighted in this review. Semi-synthetic polymers including ethyl cellulose ether (EC), hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC), and sodium carboxymethyl cellulose (NaCMC) are also discussed. Synthetic polymers mentioned in the review include HPMC and ethyl cellulose.

Polymers, gastroretentive drug delivery systems, floating dosage forms, HPMC, ethyl cellulose

"POLYMERS USED IN FLOATING DRUG DELIVERY SYSTEMS: AN UPDATED REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 4, page no.j251-j262, April-2024, Available :http://www.jetir.org/papers/JETIR2404933.pdf

"POLYMERS USED IN FLOATING DRUG DELIVERY SYSTEMS: AN UPDATED REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 4, page no. ppj251-j262, April-2024, Available at : http://www.jetir.org/papers/JETIR2404933.pdf