• Smita.A.Navale
• Komal.S.Patil
• Dattatray.D. Valekar
• Omkar.H.Shelke
• Mahesh N. Pingale

Objectives: The goal of this study is to create and test a UV-Spectrophotometric method for estimating Rosuvastatin in bulk and pharmaceutical dosage forms utilizing a green solvent. Method: Development of UV-Spectrophotometric method was carried out by using 2.5% Sodium citrate solution as green solvent. Rosuvastatin was detected at a wavelength of 229nm. According to ICH guidelines, the developed technique was verified in terms of linearity, precision, accuracy, and robustness. Rosuvastatin in pharmaceutical dose forms was successfully estimated using a newly developed and verified approach. Results: Rosuvastatin has a maximum absorption wavelength of 229nm. In the concentration range of 5-20µg/ml, Beer’s law was fallowed the recovery of Rosuvastatin Calcium in tablet form was found to be between 97 and 102 percent. Conclusion: The method was found to be simple, environment friendly, reproducible and economical and can be used for routine analysis of Rosuvastatin in bulk and pharmaceutical dosage form. The 2.5% Sodium citrate solution can be used as green solvent.

"DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETERIC TECHNIQUE FOR ESTIMATION OF ROSUVASTATIN DRUG IN BULK AND PHARMACEUTICAL DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 4, page no.k4-k12, April-2024, Available :http://www.jetir.org/papers/JETIR2404A03.pdf

"DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETERIC TECHNIQUE FOR ESTIMATION OF ROSUVASTATIN DRUG IN BULK AND PHARMACEUTICAL DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 4, page no. ppk4-k12, April-2024, Available at : http://www.jetir.org/papers/JETIR2404A03.pdf