• Gyati Shilakari
• B. Srilatha,
• T.K.T.S, Krishna
• B. Sadhana

Nanoemulsion represent a cutting-edge approach for enhancing the bioavailability of both hydrophobic and hydrophilic drugs, as well as those susceptible to high first-pass metabolism. These colloidal systems, typically comprising oil, surfactant, and an aqueous phase, demonstrate isotropic clarity and either thermodynamic or kinetic stability, with droplet sizes ranging from 10 to 500 nanometers. The utilization of nanoemulsions (NE) facilitates sustained or controlled release of drugs and bioactive ingredients, effectively overcoming challenges associated with drug instability or poor solubility. These systems are primarily prepared using either high-energy or low-energy methods. Characterization and assessment of NE involve various parameters including particle size, zeta potential, and refractive index, among others. NE can be administered through different routes such as orally, topically, intravenously, intrapulmonary, intranasally, and intraocularly. Furthermore, they can be formulated into a variety of dosage forms including gels, creams, foams, aerosols, and sprays, employing cost-effective standard operating procedures. This review concentrates on recent advancements in nanoemulsion development and its final application.

Nanoemulsion, preparation methods, characterization, applications.

"NANOEMULSION: PRESENT PROSPECTS AND APPLICATION IN DRUG DELIVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 4, page no.o357-o372, April-2024, Available :http://www.jetir.org/papers/JETIR2404F53.pdf

"NANOEMULSION: PRESENT PROSPECTS AND APPLICATION IN DRUG DELIVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 4, page no. ppo357-o372, April-2024, Available at : http://www.jetir.org/papers/JETIR2404F53.pdf