• Ms. Pooja Suhas Kashid
• Dr. Uttam Singh Baghel

The skin is one of the biggest and easiest organs in the human body to access. There are three primary layers that make up skin: Epidermis, Dermis, Hypodermis or subcutaneous fat layer. The primary three roles of the skin are sensibility, regulation, and protection. The term "Percutaneous absorption" refers to the process by which chemicals enter the body through the skin and enter the systemic circulations. There are three possible points of entrance into the skin: transcellular, intercellular and transfollicular routes. Several factors affect transdermal permeability like biological factors, physicochemical factors and formulation characteristics. The current review tries highlights some basics of skin and drug absorption through the skin with factors affecting the same.

Skin, Epidermis, Protection, Percutaneous Absorption.

"THE SKIN: A PROMISING ROUTE FOR DRUG DELIVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 4, page no.q515-q523, April-2024, Available :http://www.jetir.org/papers/JETIR2404H61.pdf

"THE SKIN: A PROMISING ROUTE FOR DRUG DELIVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 4, page no. ppq515-q523, April-2024, Available at : http://www.jetir.org/papers/JETIR2404H61.pdf