• ANJALI SHARMA
• ASHISH KUMAR MISHRA

Diarrhoea is typically a sign of intestinal disorders, which can be brought on by a wide range of bacterial, viral, and parasitic (protozoa and helminths) organisms (including E. coli, Vibrio cholerae, Shigella species, and others). According to ethnopharmacological research, L. camara has been shown to have antibacterial, antifungal, and anthelmintic properties against those microorganisms that cause diarrhoea. Additionally, it has properties that are antimycobacterial, antioxidant, antinociceptive & anti-inflammatory, antimalarial, antiulcerogenic, and anti-leishmaniasis. The leaves of L. camara and its components (Lanthadne A) have been shown in in vivo investigations to exhibit antimotility and anti-diarrhoeal action in mice model of diarrhoea. Additionally, an in vitro investigation on an excised rat ileum revealed this plant has antispasmodic activity by opposing the effects of acetylcholine and compounds that can reduce gastrointestinal muscular spasm have been hypothesised to have antidiarrheal properties. Since ancient times, people all over the world have employed plants and plant extracts in homoeopathic medicines, herbal treatments, and traditional therapies. The raw medications made from various medicinal plant components have a variety of therapeutic characteristics. The study of phytochemicals based on ethnopharmacological data is widely regarded as an efficient method for discovering novel bioactive principles. Therefore, there is a perceived need to find innovative drugs that are less expensive, less expensive economically, and have fewer severe side effects.

E.Coli, Vibrio, Diarrhoea, Antimotility.

"A REVIEW ON ANTI-DIARRHOEAL ACTIVITY OF CAPPARIS ZEYLANICA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 5, page no.c272-c279, May-2024, Available :http://www.jetir.org/papers/JETIR2405233.pdf

"A REVIEW ON ANTI-DIARRHOEAL ACTIVITY OF CAPPARIS ZEYLANICA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 5, page no. ppc272-c279, May-2024, Available at : http://www.jetir.org/papers/JETIR2405233.pdf