• Shweta Vinayak Rane
• Priyanka Baban Khedekar
• Namrata Devidas Dhote
• Dhanshree Ramesh Bawane
• Vinay Vishnudas Sarode

ABSTRACT: Celecoxib is a selective COX-2 inhibitor. The way non-steroidal anti-inflammatory drugs (NSAIDs) function is by blocking the COX enzyme, which is an inflammatory mediator. Osteoarthritis, rheumatoid arthritis, and primary dysmenorrhea are all treated with celecoxib. Therefore, the main objective of this work is to examine celecoxib in pharmaceutical and biological formulations using both qualitative and quantitative methods. In this review paper, we have compiled the methodologies for estimating celecoxib based on liquid chromatography- mass spectroscopy (LC-MS), high-performance liquid chromatography (HPLC), and UV/Vis spectroscopy. Furthermore, we have discussed the bioanalytical methods for CXB analysis. To sum up, this review article will assist researchers in developing new methods for estimating drug concentrations in biological fluids and pharmaceutical dose forms.

Celecoxib, Analytical method, High-performance liquid chromatography, liquid chromatography-mass spectroscopy, Bioanalytical methods

"Advances in Analytical and Bioanalytical Methods for Celecoxib Determination: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 5, page no.o723-o735, May-2024, Available :http://www.jetir.org/papers/JETIR2405F85.pdf

"Advances in Analytical and Bioanalytical Methods for Celecoxib Determination: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 5, page no. ppo723-o735, May-2024, Available at : http://www.jetir.org/papers/JETIR2405F85.pdf