• Dr. MANISHA SINGHAL

In medicinal research area the search for new antibacterials is always an objective of many researchers. But the major problem associated with it is that antibacterials sometime cause side effects and resistance also develops to them in course of time. So it is need of time that there should be continuous research for antibacterials as well as drugs of other properties too. Thiazole and its derivatives are the category of heterocyclic compounds showing various biological activities. The purpose of this review paper is to orient the researchers for the design and synthesis of some new compounds containing thiazole core and developing more efficient and safer drugs. Many efforts are done for synthesising compounds containing thiazole core having enhanced biological activities and synthesising them in high yield to make medicinal studies and clinical uses. Molecules containing the thiazole core possess wide range of biological properties like anti-cancer, anti-inflammatory anti-bacterial , Diuretic activity, antithelmintic etc. This review briefs the pharmacological importance and various synthetic routes regarding the synthesis of thiazoles and their derivatives.

Thiazole, anti-inflammatory, antibacterial, anti-cancer, antithelmintic

"THIAZOLE AND ITS DERIVATIVES: MEDICINAL IMPORTANCE AND VARIOUS ROUTES OF SYNTHESIS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 7, page no.h143-h158, July-2024, Available :http://www.jetir.org/papers/JETIR2407719.pdf

"THIAZOLE AND ITS DERIVATIVES: MEDICINAL IMPORTANCE AND VARIOUS ROUTES OF SYNTHESIS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 7, page no. pph143-h158, July-2024, Available at : http://www.jetir.org/papers/JETIR2407719.pdf