• Ms.YAGNA PATEL

Antimicrobial resistance and urinary tract infections are still the most common problems causing high social and health costs, especially in developing countries. Escherichia coli is the gram-negative bacteria that usually causes this infection. The uncontrolled and widespread use of antibiotics is causing a radical change in the resistance patterns of uropathogens. Antibiotic resistance is increasingly treated in outpatient urinary tract infections. Clinicians must be aware of the specific clinical and epidemiologic risk factors for infections caused by multidrug-resistant (MDR) uropathogens, as treatment options for these pathogens are limited. According to published studies, fosfomycin and nitrofurantoin are effective against most MDR Escherichia coli urinary tract infections. Clinical efficacy of trimethoprim-sulfamethoxazole persists despite increasing resistance worldwide. Beta-lactams have the highest resistance and the lowest clinical success rates. Resistance to fluoroquinolones is high among MDR uropathogens and is not recommended for use primarily in the treatment of urinary tract infections. In addition to consideration of local resistance, consideration of the patient's risk factors and principles of pharmacological resistance help guide optimal empiric therapy in outpatient therapy.

Uropathogen, antibiotic resistance, urinary tract infections, treatment of UTIs

"Review on Basics of antibiotic resistance in uropathogens and implications for Urinary Tract Infection treatment.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 10, page no.c586-c601, October-2024, Available :http://www.jetir.org/papers/JETIR2410362.pdf

"Review on Basics of antibiotic resistance in uropathogens and implications for Urinary Tract Infection treatment.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 10, page no. ppc586-c601, October-2024, Available at : http://www.jetir.org/papers/JETIR2410362.pdf