• Dr. Khuspe Apurva
• Dr Akshata Chavan
• Dr. Jagtap Manoj

Background: The lives of the people suffering with Chronic liver cirrhosis has changed with the advent of Liver transplants. Liver transplants is on the rise in past few years due to increased incidence of NAFLD and Alcoholic liver disease, but patients with long term coagulopathy or biliary sepsis (endotoxemia) do not warrant for liver transplant or fail post-transplant in most cases. Their line of treatment for cirrhosis does not reverse the organ damage but treat decompensation symptomatically. Here the Evolved Ancient wisdom of Ayurveda plays a major role that mentions Raktadhatu chikitsa in Liver cirrhosis. There is Rakta dhatu dushti in Yakrut dushti, as Yakrut is the moola sthana of Raktavaha strotas and Raktadhara Kala. We aimed to study the concept of Raktadhara Kala by comparing it with the endothelium. Method: The is a review on the various research articles on Kala sharir and coagulopathy in Liver cirrhosis. The concept of Kala Sharir was reviewed from ancient texts, and an inference was drawn. Conclusion: We found that in Liver cirrhosis there is coagulopathy due to endothelial dysfunction and can be compared with Raktadhara Kala. Further research in this area could lead to new insights into the functioning of the human body and the development of new therapies

Liver cirrhosis, coagulopathy, kala, endothelial dysfunction, Rakta dhatu dushti

"A Review On Endothelial Dysfunction In Liver Cirrhosis w.r.t Raktadhara Kala", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 10, page no.f430-f437, October-2024, Available :http://www.jetir.org/papers/JETIR2410540.pdf

"A Review On Endothelial Dysfunction In Liver Cirrhosis w.r.t Raktadhara Kala", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 10, page no. ppf430-f437, October-2024, Available at : http://www.jetir.org/papers/JETIR2410540.pdf