• Ishfaq Ahmad Malik
• Anil J. Gour
• Mushtaq Ahmad Dar
• Mehak Naseer Mir
• Rayees Ahmad Naik

Pretilachlor (PTC) is a systemic herbicide of the chloroacetamide group that is used to reduce weeds in rice fields. The present study investigated the harmful effects of the herbicide pretilachlor (LC50) at 96 hours on changes in hematological parameters (total Hb, white blood cell (WBC), and red blood cell (RBC) counts) and protein contents (gill, liver and muscle) in the fish common carp (Cyprinus carpio)). The common carp is the third most extensively farmed and significant freshwater fish species worldwide in terms of commerce. This fish contributes to a healthy diet for humans and is a rich source of nutrients. When exposed to the herbicide pretilachlor at sublethal doses (10% and 30%), the RBC and Hb contents tended to decrease in comparison with those of the control, but the WBC analysis indicated a substantial increase. The toxicity of pretilachlor caused a decrease in total protein at all concentrations throughout all the time periods. The gill tissue presented the lowest overall protein level, whereas the muscles presented the highest protein concentration. The decrease became more noticeable as the exposure time increased. The overall protein level decreased in all tissues as the exposure time increased in comparison with that of the control during exposure times of 4, 8, and 12 days. The results showed that the herbicide pretilachlor was harmful at sublethal amounts. Thus, we can deduce that fish are poisoned by the pesticide pretilachlor. As a result, the findings of this study may lead to the discovery of a natural remedy to lessen the impact of herbicides on fish, and excessive application should be prevented.

fish, Cyprinus carpio, Herbicide, Pretilachlor (PTC), Haematology, Hb, RBC, WBC, Total protein.

"Effect of Pretilachlor A Chloroacetamide Herbicide on Some Haematological Parameters And Protein Alterations In The Fresh Water Fish, Cyprinus Carpio (Linnaeus)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 10, page no.f836-f846, October-2024, Available :http://www.jetir.org/papers/JETIR2410589.pdf

"Effect of Pretilachlor A Chloroacetamide Herbicide on Some Haematological Parameters And Protein Alterations In The Fresh Water Fish, Cyprinus Carpio (Linnaeus)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 10, page no. ppf836-f846, October-2024, Available at : http://www.jetir.org/papers/JETIR2410589.pdf