• Lokesh sharma
• Lokesh sharma
• Dr Reena Singh
• Roshan Zehra

The transdermal drug delivery system (TDDS) has emerged as a significant advancement in pharmaceutical sciences, offering a non-invasive route for systemic drug administration. By circumventing the gastrointestinal tract and hepatic first-pass metabolism, TDDS provides controlled and sustained drug release. This review elaborates on its mechanisms, components, advantages, limitations, types, recent innovations, and applications, with references supporting each statement.

Transdermal Drug Delivery System Skin penetration Stratum corneum Drug absorption pathways Controlled drug release

"A Comprehensive Review on Transdermal Drug Delivery Systems (TDDS)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 11, page no.g351-g356, November-2024, Available :http://www.jetir.org/papers/JETIR2411633.pdf

"A Comprehensive Review on Transdermal Drug Delivery Systems (TDDS)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 11, page no. ppg351-g356, November-2024, Available at : http://www.jetir.org/papers/JETIR2411633.pdf