• C.Renuka thejeshwini
• Chetla Varshitha

Abstract Wounds associated with diabetes are more complex and difficult to treat, this is because they are generally difficult to heal, and if left untreated, they lead to a lot of severe complications not forgetting the fact that they generate more costs than any other wound in the health facilities .This paper aims at examining the synthesis of multifunctional self –healing hydrogels for improvement of diabetic wound healing with the developed hydrogels releasing growth factors and antimicrobial agents to the affected area while at the same time having selfhealing properties that alter with the healing process .vivo and invitro tests portraying enhanced cell response, tissue generation rate as well as efficient anti-infection mechanisms superior to general dressings improved cellular responses, accelerated tissue regeneration and effective infection management compared to conventional dressings. The results presented point toward the potential of these innovative hydrogels as a true game-changer for diabetic wounds management as well as patients’ treatment prognosis enhancement. Future studies of this hydrogel will concentrate on modulating the chemical makeup and evaluating the long-term performance. the ability of these hydrogels to maintain a moist wound environmental crucial for promoting cellular migration, collagen formation, angiogenesis-critical processes in wound healing. The self-healing and adaptive characteristics of these hydrogels can also reduce the need for frequent dressing changes improving patient comfort and reducing healthcare costs. The integration of these multifunctional materials into wound care has the potential materials into wound care has the potential to revolutionize diabetic wound management, providing more effective, and patient-friendly solution multifunctional self-adaptive hydrogels offer an innovative and promising approach to address the challenges of diabetic wound healing, improving both the quality and speed of recovery for affected patients.

Keywords: Hydrogel, diabetic wound, chronic wound, wound microenvironment, wound healing,

"Enhancing diabetic wound healing with multifunctional self adaptive hydrogels ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 12, page no.a83-a102, December-2024, Available :http://www.jetir.org/papers/JETIR2412009.pdf

"Enhancing diabetic wound healing with multifunctional self adaptive hydrogels ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 12, page no. ppa83-a102, December-2024, Available at : http://www.jetir.org/papers/JETIR2412009.pdf