• Idris Baba Mai-Garba
• Mohammed Musa Lawan
• Zainab Umar Baba

This study is an evaluation of heavy metals concentration (lead, cadmium, and arsenic) and some biochemical markers (urea and creatinine) in blood and urine specimens collected from more than one hundred (100) subjects at Yobe State University Teaching hospital, Damaturu. A group of chronic kidney disease (CKD) patients were included in addition to a control group. The experimental results showed much higher levels of heavy metals in patients with CKD. Female CKD patients had arsenic concentrations of 0.938 ± 0.05 mg/L in blood and 0.8442 ± 0.04 mg/L in urine, cadmium levels of 1.0681 ± 0.06 mg/L in blood and 0.38976 ± 0.03 mg/L in urine. Male CKD patients showed blood cadmium levels of 0.971 ± 0.05 mg/L and urine cadmium levels of 0.928 ± 0.04 mg/L. The control group demonstrated notably lower concentrations, with females showing blood cadmium levels of 0.092 ± 0.01 mg/L and urine lead levels of 0.102 ± 0.02 mg/L. Biochemical markers in CKD patients revealed urea levels of 120.0 ± 10.0 mg/dL for females and 130.0 ± 12.0 mg/dL for males, while creatinine levels were 3.0 ± 0.3 mg/dL and 3.5 ± 0.4 mg/dL for females and males, respectively. These findings suggest a potential correlation between heavy metal exposure and renal dysfunction, underscoring the need for preventive measures to mitigate environmental and occupational exposure risks

Chronic Kidney Disease, Heavy metals

"Determination of Heavy Metals in Blood and Urine of Chronic Kidney Disease (CKD) Patients at YSUTH, Damaturu", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 12, page no.a665-a675, December-2024, Available :http://www.jetir.org/papers/JETIR2412059.pdf

"Determination of Heavy Metals in Blood and Urine of Chronic Kidney Disease (CKD) Patients at YSUTH, Damaturu", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 12, page no. ppa665-a675, December-2024, Available at : http://www.jetir.org/papers/JETIR2412059.pdf