• Bhuvaneshwari Shrikrushna Bhoir
• Dr.Manisha Nangude
• Akash Nalawade
• Madhura Bhoir
• Gaurav Bhurkud

Extended release(ER) formulations are designed to release medicines sluggishly over time, keeping up remedial situations and reducing dosing. Excipients play a pivotal part in ER formulations, impacting medicine release, stability, and bioavailability. This review discusses the types of recipients(binders, paddings, disintegrate, lubricants, and coatings), mechanisms of medicine release(prolixity, corrosion, bibulous processes, and swelling), and factors affecting medicine release solubility, permeability, and expression parameters). Regulatory considerations, stability testing, and emerging trends in expression development using biodegradable polymers and advanced manufacturing emerging 3D printing) are also stressed. Understanding recipient relations with targets can lead to individualized drug and new remedial targets. This review provides a comprehensive overview of ER formulations and the significance of excipients in optimizing medicine delivery systems.

Extended release formulation, excipients, medicine delivery systems, 3D printing,

"Investigating the role of excipients in modulating drug release from extended release formulations", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 12, page no.f609-f618, December-2024, Available :http://www.jetir.org/papers/JETIR2412568.pdf

"Investigating the role of excipients in modulating drug release from extended release formulations", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 12, page no. ppf609-f618, December-2024, Available at : http://www.jetir.org/papers/JETIR2412568.pdf