• Sakshi Kawale
• Rutika Karad
• Tejaswini Khairnar
• Shruti Kapadne
• Pankaj Aher

The usage of prebiotics and probiotics for the preservation as well as the enhancement of gut health has gained popularity. Prebiotics are food components which cannot be utilized by the human body but help in the growth of good bacteria of the intestine while probiotics are defined as live bacteria that have positive effects to their hosts by standing in for or altering the balance of the gut microbiota. This review highlights the need for usage of prebiotics and probiotics to maintain the gut health, their mechanisms, their clinical uses and what is to be expected in the future. Many prebiotics, including inulin and fructooligosaccharides (FOS), are a source of nutrition for the beneficial bacterial populations in the colon, such as Bifidobacteria responsible for the synthesis of short-chain fatty acids (SCFAs) which have sterilizing effects in the colon. Probiotics are also effective and inhibitory methods especially the Lactobacillus and Bifidobacterium Probiotics for the management of IBS, IBD and antibiotic-associated diarrhoea. Mechanisms of probiotics include the colonization of a subject’s gut, inhibition of pathogens, and immune response modulation. However, there are issues that still exist such as strain specificity, dosage inconsistency among others which suggest that more studies ought to be carried out. This review states that prebiotics and probiotics are promising instruments for the maintenance of health of the gut, although, to achieve their maximum effect in practice, a reasonable tailored prescription is warranted.

Prebiotics, Probiotics, Gut health, Clinical applications, Immune modulation, personalized medicine.

"Uses of Probiotics and Prebiotics in Gut Health", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 12, page no.g575-g588, December-2024, Available :http://www.jetir.org/papers/JETIR2412665.pdf

"Uses of Probiotics and Prebiotics in Gut Health", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 12, page no. ppg575-g588, December-2024, Available at : http://www.jetir.org/papers/JETIR2412665.pdf