• Ms. Sana Tahreem Moiez Shaikh
• Mr. Akshay Madhukar Roman
• Dr. Vandana P. Patil
• Dr. S. S. Angadi

Tridax procumbens, a globally prevalent weed and an integral part of traditional Ayurvedic medicine, exhibits diverse pharmacological properties due to its rich phytochemical composition. This review consolidates the therapeutic potential of T. procumbens across various domains, highlighting its antimicrobial, antioxidant, anti-inflammatory, wound healing, hepatoprotective, antidiabetic, anticancer, anti-ulcer, analgesic, antimalarial, hair growth-promoting, and neuroprotective activities. The plant's bioactive compounds, including alkaloids, flavonoids, tannins, glycosides, sterols, polyphenols, and vitamins, contribute to its multifunctional applications. The antimicrobial activity is particularly noteworthy, targeting various bacterial strains, while its antioxidant properties, linked to phenolic compounds, play a crucial role in mitigating oxidative stress and facilitating wound healing. Anticancer studies reveal significant tumour-suppressive effects, particularly in breast and prostate cancer models. Additionally, T. procumbens demonstrates hepatoprotective effects by reducing oxidative stress and promoting liver cell regeneration. Its anti-inflammatory and analgesic effects are mediated through molecular pathways involving COX-2 and TNF-α. Despite these promising results, most studies are limited to in vitro or preclinical models. Further research is required to elucidate detailed molecular mechanisms, optimize bioactive compound extraction, and evaluate clinical efficacy through human trials. Additionally, the development of novel drug delivery systems and standardized formulations can enhance its therapeutic potential and market viability. This review underscores the need for advanced pharmacological investigations and sustainable utilisation of T. procumbens. With its extensive pharmacological profile and promising therapeutic potential, T. procumbens emerges as a valuable candidate for drug discovery and development, offering opportunities for integration into modern medicine.

Tridax procumbens L., Wound healing, Anti-cancer, Ayurvedic medicine, Anti-oxidant, Anti-inflammatory, Natural product pharmacology

"Tridax procumbens: A Weed Turned Wonder - Exploring Its Therapeutic Versatility and Pharmacological Promise", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 1, page no.e414-e430, January-2025, Available :http://www.jetir.org/papers/JETIR2501456.pdf

"Tridax procumbens: A Weed Turned Wonder - Exploring Its Therapeutic Versatility and Pharmacological Promise", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 1, page no. ppe414-e430, January-2025, Available at : http://www.jetir.org/papers/JETIR2501456.pdf