• Shital Eknath Susar
• Satish Gajanan Lodhe
• Dr.Shivshankar Mhaske

: the term “phyto” means plant while “some” means cell-like. Phytosomes are bioactive phytoconsituents of herb extract surrounds and bound by a lipid. Most of the bioactive constituents of phytomedicines are water-soluble compounds like flavonoids, glycosides; terpenoids in which flavonoids are a major class of bioactive compounds possesses broad therapeutic activities .Novel drug delivery system is a novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. Our country has a vast knowledge base of Ayurveda whose potential is only being realized in the recent years. The effectiveness of any herbal medication is dependent on the delivery of effective level of the therapeutically active compound. The phytosome technique reduces these tasks to reasonable extents. The phytosome or Herbosome technique increases the hydrophilicity of highly lipophilic drug there by making it suitable for drug delivery and increases the lipophilicity of hydrophilic phytoconstituents adequately to cross biological membrane. The topical application of phytosomes for cosmetic purpose has already been proven. This review also contains a comparative account of liposomes and phytosomes along with recent advancements in the field of phytosome technology with a special concern to transdermal drug delivery.improved forms of herbal formulation which contain the bioactive phytoconstituents of herb essence enclosed and bound by a lipid.

: Phytosomes; Bioavailability, Phospolipids, phytoconstituents , Herbosomes; Plant extract, Drug delivery, Phosphatidylcholine

"Phytosomes In The Fild Of Novel Drug Delivery System", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 1, page no.e686-e690, January-2025, Available :http://www.jetir.org/papers/JETIR2501489.pdf

"Phytosomes In The Fild Of Novel Drug Delivery System", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 1, page no. ppe686-e690, January-2025, Available at : http://www.jetir.org/papers/JETIR2501489.pdf