• Aditya Sinha
• Ashish
• Alok kumar

Nutraceuticals derived from food sources, nutraceuticals combine pharmacological and nutritional characteristics to offer health benefits beyond simple nutrition. This paper explores the importance of synergy in enhancing the efficacy of nutraceuticals, particularly in managing complex health conditions. Curcumin and piperine are two examples of synergistic combos that show improved bioavailability and complementary processes that can lead to better health outcomes. Challenges such as poor solubility, rapid metabolism, instability, and dietary interactions hinder the bioavailability of many nutraceuticals. Piperine has been identified as a significant enhancer of curcumin absorption by inhibiting metabolic enzymes and increasing intestinal permeability. These synergistic interactions not only improve bioavailability but also amplify therapeutic effects in conditions like arthritis and cancer. Continued research into optimal combinations and dosages is essential for maximizing the health benefits of nutraceuticals and informing public health strategies.

"Synergistic effect of nutraceuticals ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 1, page no.e289-e303, January-2025, Available :http://www.jetir.org/papers/JETIR2501534.pdf

"Synergistic effect of nutraceuticals ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 1, page no. ppe289-e303, January-2025, Available at : http://www.jetir.org/papers/JETIR2501534.pdf