• Vivekanandhan Gayathri
• Ragamalika. S
• Rajasekar. T
• Devi. B
• Haritha. S

Diseases caused by bacterial infections, especially drug-resistant bacteria have threatened human health throughout the world. It has been predicted that early diagnosis and therapy will efficiently decrease the mortality rate caused by bacterial infections. Therefore it is urgent to develop effective methods for the early detection for bacterial infections and treat them as soon as possible. Some bacteria can be used for the treatment of bacterial infections such as Escherichia coli (E. Coli), Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella spp, Klebsiella pneumoniae, Mycobacterium tuberculosis, Streptococcus pyogenes, Enterococcus faecalis, Helicobacter pylori. Nanotechnology-driven approaches using nanoparticles can selectively target and destroy intracellular pathogenic bacteria, overcoming conventional drug delivery challenges. Nanoparticles are increasingly being effective for the treatment of bacterial infections due to their unique properties, such as high surface area-to-volume ratio and the ability to be functionalized for targeted delivery. Nanoparticles like polymeric micelles, nanoliposomes, and metal nanoparticles enhance drug bioavailability, stability, and targeting, improving therapeutic effectiveness and minimizing side effects. Even nanoparticles like Silver Nanoparticles (AgNPs), Gold Nanoparticles (AuNPs), Zinc Oxide Nanoparticles (ZnO NPs), Copper Nanoparticles (CuNPs), Iron Oxide Nanoparticles (Fe3O4 NPs), Chitosan Nanoparticles, Titanium Dioxide Nanoparticles (TiO2 NPs), Graphene Oxide Nanoparticles, Silica Nanoparticles, Polymeric Nanoparticles can also be very useful for treatment of bacterial infections as they can encapsulate antibiotics or antimicrobial agent to provide sustained release and targeted delivery to bacterial infections. (Xu et al., 2019)

Bacterial infections, Drug Delivery, Nanoparticles, Antibiotic agents, Drug targeting.

"Targeted Antibiotic Delivery Using Nanoparticles in the Diagnosis and Treatment of Bacterial Infections ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 1, page no.g676-g691, January-2025, Available :http://www.jetir.org/papers/JETIR2501674.pdf

"Targeted Antibiotic Delivery Using Nanoparticles in the Diagnosis and Treatment of Bacterial Infections ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 1, page no. ppg676-g691, January-2025, Available at : http://www.jetir.org/papers/JETIR2501674.pdf